- Country: USA
- Genres: Comedy, Family
- Release: 2010-06-04
- Director: Tom Dey
- Writers: Tim Rasmussen , Vince Di Meglio , Brad Anderson , Phil Leeming
- Language: English
- Stars: Owen Wilson
(I) , Judy Greer , Lee Pace , Emma Stone
- Runtime: 87 min
- Awards: 3 nominations.
- AKA: Marmaduke (Brazil) , Marmadjuk (Serbia) , Marmaduke (Argentina) , Sansone (Italy) , 酷狗馬馬杜 (Taiwan) , Marmaduke (Australia) , Marmaduke , Мармадьюк (Russian Federation) , Marmaduke (Greece) , Marmaduke (Spain) , Marmadukas (Lithuania) , Marmaduke - pies na fali (Poland) , Мармадюк (Bulgaria) , Marmaduke (Canada) , サーフィン ドッグ (Japan) , Marmaduke (Portugal, Portuguese Republic) , Marmaduke - A kutyakomédia (Hungary) , Çılgın Köpek (Turkey) , Marmaduke (United Kingdom) , Marmaduke (United States of America)
- Plot: Marmaduke, the world's most lovable Great Dane, leaps from comic strip fame (appearing in 600 newspapers in over 20 countries) to big screen stardom in this family comedy event. A suburban family moves to a new neighborhood in Orange County, California with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way. But it's not all living large for the Duke, who finds that fitting in with his new four-legged friends - and a potential romantic interest - isn't always easy for a super-sized teenage dog. Owen Wilson gives the beloved Great Dane his voice in the film, which also features the voices of Fergie, George Lopez, Emma Stone and Kiefer Sutherland.
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