- Gender: Male
- Birthday: 1864-10-28
- Day of Death: 1927-09-20 ( 63 years old )
- Place of Birth: Rockford, Illinois, USA
- Also Known As: George O. Nicholls / George Nicholls / George O. Nichols / G.O. Nichols
George Nichols (1864 – September 20, 1927) was an American actor and film director. He appeared in 221 films between 1908 and 1928. He also directed 103 films between 1911 and 1916.